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Its effects are very similar to those of the popular, now-banned substance ephedrine. However, the effects of clenbuterol tend to be longer-lasting and slightly stronger. This substance often causes a slight increase in body temperature, an elevated heart rate, and mild anxiety. It also increases the rate at which fats and proteins are used in the body, making its effectiveness as a fat burner evident.

Clenbuterol is also effective as a respiratory aid. Users often report being able to sustain cardio sessions for much longer periods because of this. This effect is also very helpful for a bodybuilder trying to cut fat to get into competition shape. Some Clenbuterol users claim it has mild anabolic properties as well. This is usually attributed to the increased strength often felt shortly after administration. However, it is more likely that this is due to the drug's stimulant effect rather than any anabolic activity.

Clenbuterol acts quickly on receptors, and for this reason, it is often recommended to use it for two weeks, then take a two-week break to allow the receptors to recover. If this is not done, the body can become accustomed to the drug and its effects will diminish.

Bodybuilders should ensure they drink plenty of water when taking Clenbuterol and never take more than three tablets per day. Most prefer to take their tablets in the morning to allow the effects time to subside before bedtime. Those with a history of heart problems should not use Clenbuterol. Women can also take Clenbuterol, but at lower doses.